Cancer clinical trials continue to improve how cancer is treated, managed, and understood across many cancer types. On World Cancer Day, global awareness efforts highlight not only prevention and early detection, but also the research studies that help strengthen cancer care for people living with the disease.
Cancer affects millions of individuals and families every year. While treatment options have improved significantly, there is still a need for safer therapies, better supportive care, and new treatment approaches for advanced cancers. Clinical research helps answer these important questions and supports steady progress in oncology.
Every improvement in cancer care begins with a clinical study. These studies follow strict safety standards, ethical guidelines, and informed consent processes. Participation is always voluntary. By understanding how research works, patients and caregivers can feel more confident when reviewing available options.
Below, we highlight five active cancer clinical trials and explain the purpose of each study in clear, simple terms.
1. Improving Balance, Strength, and Physical Function in Older Adults With Cancer
Study Name: COBRA Cancer, Older Adults, Balance and Resistance Activities
Cancer treatment can sometimes lead to weakness, fatigue, and balance issues, especially in older adults. This study evaluates whether a structured strength and balance exercise program can safely improve physical function in older adults living with cancer.
The main purpose of this trial is to see whether guided resistance and balance exercises can help reduce fall risk and improve daily mobility. Researchers are also studying whether this type of digital exercise program is practical and safe during cancer treatment.
Participants follow a guided program over several weeks, and researchers measure changes in strength, balance, and overall physical ability.
Why this matters
Improving balance and strength may help older adults maintain independence and feel more confident in their daily activities.
Locations
This study is currently recruiting at 6 research locations in the United States.
Learn more about the study and check your eligibility here.
2. Evaluating Long Term Targeted Treatment for Solid Tumors
Study Name: A Study to Test Long Term Treatment With Brigimadlin in People With Solid Tumours
This study focuses on people with solid tumors who previously received a medicine called brigimadlin in an earlier clinical trial. Researchers are continuing to evaluate this treatment to better understand its long term safety and effectiveness.
The main purpose of this study is to determine whether brigimadlin remains safe when taken over an extended period. Researchers are also assessing whether continued treatment helps keep cancer stable or under control.
Participants continue treatment while doctors monitor their health and track how their cancer responds over time.
Why this matters
Long term safety data is essential before a treatment can become widely available for broader patient use.
Locations
This study is currently recruiting at 50 research locations internationally.
Find additional details about this study and explore eligibility information here.
3. Testing a New Early Phase Treatment for Advanced Solid Tumors
Study Name: A Phase 1 and 2a Study of BMS 986517 in Participants With Advanced Solid Tumors
This study is testing a new investigational medicine in people whose solid tumors have progressed despite standard treatments.
The main purpose of this trial is to determine the safest dose of this new medicine and understand how the body responds to it. Researchers are also looking for early signs that the treatment may slow tumor growth.
Because this is an early phase study, safety monitoring is very detailed and ongoing.
Why this matters
Early phase cancer clinical trials are the first step in developing new treatment options for future patients.
Locations
This study is currently recruiting at 19 research locations.
Review study information and learn how participants can take part.
4. Understanding Long Term Outcomes From Radiation Therapy
Study Name: The Radiation Oncology Registry and Biosample Repository
This study collects information from individuals who are receiving radiation therapy as part of their cancer care. It does not test a new treatment. Instead, it gathers long term data to better understand outcomes.
The main purpose of this registry is to track how radiation therapy affects patients over time. Researchers are studying side effects, treatment patterns, and long term results to help improve future radiation care.
Participants continue their planned radiation therapy while researchers collect treatment information.
Why this matters
Real world data from registry studies helps doctors refine treatment approaches and improve patient safety.
Locations
This study is currently recruiting at 4 research locations in the United States.
Explore this study further and understand the next steps for participation.
5. Evaluating a New Investigational Medicine in Advanced Solid Tumors
Study Name: A Phase 1 Study of NM6603 in Advanced Solid Tumors
This Phase 1 study is testing a new investigational medicine called NM6603 in people with advanced solid tumors.
The main purpose of this study is to determine the safest dose and understand possible side effects. Researchers are also looking for early signals that the medicine may affect tumor growth.
Early stage trials focus on safety first before moving into larger studies.
Why this matters
Every new cancer therapy begins with early phase cancer clinical trials that establish safety and guide future development.
Locations
This study is currently recruiting at 4 research locations in the United States.
Access more information about this study and review participation criteria.
How Clinical Studies Help Improve Cancer Care
Cancer clinical trials support progress across supportive care, targeted treatments, early phase drug development, and long term outcome research. Each study helps answer specific questions that strengthen how cancer is treated and managed.
Participation is always voluntary. Eligibility depends on factors such as cancer type, stage, previous treatment, and overall health. Individuals interested in exploring research options should discuss them with their healthcare provider.
Resources such as clinical trial listings by medical condition can help patients explore publicly available studies in a structured way. Educational insights and cancer research awareness articles are also available through the DecenTrialz blog. Dedicated sections provide resources for advocacy groups and information for healthcare professionals. Those who would like to learn more about the organization can visit the About page or contact our team for general questions.
Moving Cancer Research Forward on World Cancer Day
World Cancer Day emphasizes prevention, awareness, access to care, and continued research. Cancer clinical trials remain essential in developing safer treatments, improving supportive care, and expanding understanding of how cancer behaves.
By staying informed and supporting research awareness, patients and communities contribute to the continued advancement of cancer care for future generations.
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