Cervical cancer clinical trials recruiting participants play a critical role in advancing prevention, screening, and care. Cervical cancer is one of the most preventable cancers, yet it continues to affect thousands of people each year.
In the United States, more than 11,000 people are diagnosed with cervical cancer annually. Persistent infection with high-risk types of human papillomavirus (HPV) is the primary cause, making vaccination and screening powerful tools for prevention. Still, gaps remain, in early detection, access to screening, and treatment options for those who are diagnosed.
That is why clinical research plays such a critical role. Every improvement in prevention, screening accuracy, or treatment approach begins with a clinical study. By participating in research, individuals help shape future standards of care while contributing to progress that benefits entire communities.
Below, we highlight five cervical cancer clinical studies that are helping move prevention, screening, and treatment forward, and why each one matters.
1. Improving Prevention and Early Identification of Cervical Changes
Clinical Trial: Reducing Urban Cervical Cancer Disparities
One of the greatest opportunities in cervical cancer care lies in identifying abnormal changes before cancer develops. This study focuses on strengthening prevention strategies and improving how early cervical changes are recognized.
Researchers are examining approaches that may help detect early biological signals associated with disease progression. By refining how these changes are identified, the study aims to support earlier intervention and better long-term outcomes.
Why this matters
Earlier identification often means simpler treatment, fewer complications, and improved peace of mind for individuals undergoing screening.
Locations
This study is currently recruiting participants at 3 research locations in the United States.
Learn more about the study and check your eligibility here
2. Exploring New Treatment Options for Advanced Cervical Cancer
Clinical Trial: Studying a New Treatment Compared With Standard Care for Recurrent or Metastatic Cervical Cancer
When cervical cancer returns or spreads to other parts of the body, treatment options can become more limited. This study compares a new investigational treatment with the current standard treatments typically chosen by physicians for people receiving second-line therapy.
Researchers are evaluating how this newer treatment performs when used on its own compared with commonly used care options. The goal is to better understand effectiveness and safety in people whose cancer has progressed after earlier treatment.
Why this matters
Research like this helps determine whether new treatment approaches can offer additional options for individuals with advanced cervical cancer, supporting informed decision-making and future care standards.
Locations
This study is currently recruiting participants at 232 research locations across the United States and internationally.
Find additional details about this study and explore eligibility information here.
3. Exploring New Treatment Approaches for Cervical Cancer
Clinical Trial: Comparing Two Radiation Therapy Approaches After Cervical Cancer Surgery
For individuals diagnosed with cervical cancer, treatment options continue to evolve. This study examines advanced treatment approaches that may improve effectiveness while carefully monitoring safety and patient experience.
Researchers are evaluating how newer therapies perform alongside or in place of standard treatments, with the goal of refining how cervical cancer care is delivered.
Why this matters
Treatment-focused research helps improve outcomes and supports the development of more personalized care options.
Locations
This study is currently recruiting participants at 3 research locations in the United States.
Review study information and learn how participants can take part.
4. Understanding and Managing HPV-Related Cervical Changes
Clinical Trial: Studying a New Combination Treatment for Advanced Cervical Cancer
High-risk HPV infection plays a central role in cervical cancer development, but not all HPV-related changes progress in the same way. This study focuses on how cervical changes linked to HPV can be monitored and managed more effectively.
By understanding how these changes evolve over time, researchers aim to improve guidance around follow-up care and intervention timing.
Why this matters
Clearer monitoring strategies can help avoid both delayed care and unnecessary treatment.
Locations
This study is currently recruiting participants at 3 research locations in the United States.
Explore this study further and understand the next steps for participation.
5. Evaluating Targeted Interventions in Cervical Cancer Care
Clinical Trial: Improving Access to Cervical Cancer Screening for Underserved Communities
Some cervical cancer studies focus on targeted interventions — approaches designed to act on specific biological processes involved in cancer development. This study examines how such targeted strategies perform in cervical cancer care.
Researchers aim to better understand how these approaches affect outcomes and whether they can help refine future treatment pathways.
Why this matters
Targeted research supports more individualized care and contributes to the ongoing evolution of cervical cancer treatment standards.
Locations
This study is currently recruiting participants at 1 research location in the United States.
Access more information about this study and review participation criteria.
How Clinical Studies Help Improve Cervical Cancer Prevention and Care
Clinical studies play a central role in improving how cervical cancer is prevented, detected, and treated. Research helps identify more effective screening methods, strengthens prevention strategies such as HPV testing and vaccination, and evaluates new approaches to care for those who are diagnosed.
All clinical studies follow strict ethical and safety standards, and participation is always voluntary. By taking part in research, individuals contribute to medical knowledge that helps refine prevention efforts, improve care pathways, and support better outcomes for future patients.
Moving Cervical Cancer Research Forward
Reducing the impact of cervical cancer requires continued focus on prevention, early detection, and research. Global public-health efforts emphasize HPV vaccination, routine screening, and timely treatment, with clinical studies playing a vital role in improving how care is delivered.
By learning about ongoing research and supporting clinical trial awareness, individuals help move cervical cancer care forward for future generations.